Clopidogrel and Aspirin Mechanism Action of Antiplatelet Drugs 2019

Clopidrogel and Aspirin


Clopidogrel drugs are antiplatelet drugs. Aspirin drugs are non-opioid analgesic drugs. Clopidogrel and aspirin drugs are useful for heart attacks patients. It prevents blood clots and reduces the risk of heart attacks. Clopidogrel is an antiplatelet drug. Aspirin is non-steroids anti-inflammatory drug (NSAID) and used in pain, inflammation, and fever.

Clopidogrel Mechanism of Action

It is a thienopyridine drug. Clopidogrel mechanism is to irreversibly inhibits the platelet aggregation. Clopidogrel by selection inhibits the binding of adenosine phosphate (ADP) to its platelet receptors and the subsequent ADP-mediated activation of the glycoprotein GPllb/llla complex, thereby inhibiting platelet aggregation.

Aspirin Mechanism of Action

Aspirin drugs are Acetyl Salicylic Acid drugs. Aspirin mechanism is to activate platelet in acute arterial thrombosis. Small doses of aspirin block platelet aggregation by irreversible inhibition of the platelet enzyme cyclooxygenase. Aspirin drugs block the formation of thromboxane A2. It is a pro aggregator vasoconstrictor.

Clopidogrel and Aspirin Difference

Aspirin drugs are non-steroid anti-inflammatory drugs. It is working properly for patients having fever, pain, and inflammation. Clopidogrel drugs are antiplatelet drugs. It works for patients having heart-related problems or heart attacks.

Clopidogrel drugs reduce the hero sclerotic events of the heart. In heart stroke and vascular death in patient clopidogrel drug used. It is very useful for the patients having recent heart stroke and for established peripheral arterial diseases.

Aspirin drugs are very useful for the treatment of prophylaxis patients. These having the possibility of blood clotting. For coronary bypass and heart strokes, aspirin is very effective. It is working properly for the patients having platelet disorder and other bleeding disorder.

Clopidogrel and Aspirin Side Effects

Clopidrogel has common side effects like rashes on the skin. Some patients feeling internal abdominal discomforts like constipation or diarrhea. Patients always have a risk of internal bleeding and hepatic impairment by taking clopidogrel drugs.

Taking aspirin may precipitate the bronchospasm and induce asthmatic attacks in some patients. In pregnancy don’t take aspirin drugs. Always take theses drugs with the permission of your doctor or health professional. Gastrointestinal hemorrhage or internal bleeding are two most common side effect of this drug.

Clopidogrel and Aspirin Drug Precautions

Dual therapy with clopidogrel and aspirin drugs potentiate platelets aggregation. Both these drugs are increases the risk of gastrointestinal blood loss or internal bleeding. May potentiate the effect of anticoagulants drugs.

Taking both clopidrogel and aspirin drugs orally should always talk to the doctor. If you need a pain killer should avoid clopidrogel drugs or consult your doctor before use. Heart patients should not take these drugs without the permission of doctors or health professionals. It may cause internal bleeding.

Clopidogrel and Aspirin Warnings

Both these drugs are from different groups and have a different working process. As I mentioned above that clopidogrel drugs are antiplatelet drugs and aspirin drugs are non-steroid anti-inflammatory drugs (NSAID’s). So before used these drugs together must consult your doctor and take these drugs as suggested by them.

Med Gyani

Med Gyani

My website is all about drug information for professional and consumers. Search my website for drugs, drugs information, drugs Interactions, drug dosage, drugs side effects, drugs precaution, drugs usage, health information, and science information.

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